BDBM150102 US8975417, 170
SMILES CCn1nc(C)c2C(N(C(=O)c12)c1cc(C)c(=O)n(C)c1)c1ccc(Cl)cc1F
InChI Key InChIKey=YDFGIFLYGLMJSV-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 150102
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of His-tagged CREBP (unknown origin) using acetyl-histone H4 as substrate after 35 mins by AlphaScreen assayMore data for this Ligand-Target Pair